PUBLICATIONS ( Google Scholar )


  • 116. K.K. Yang, Y.J. Liu, Y. Wang, Q.L. Ren, H.Y. Guo, M.B. Matson, X.Y. Chen*, Z.H. Nie*, Enzyme-induced in-vivo assembly of gold nanoparticles for imaging-guided synergistic chemo-photothermal therapy of tumor, 2019, Submitted.

  • 114. H.Z. Li, Q.H. Chen, D.L. Chen, L.X. Wu, Z.H. Nie, T.A. Bogetti, J.W. Gillespie Jr., Finite element modeling of nanoindentation on a microsphere supported on a flat substrate, 2019, Submitted.

  • 113. H.Y. Guo, J. Cheng, K.K. Yang, G.Y. Wu, K. Demella, T. Li,  S.R. Raghavan, Z.H. Nie*, Programming the shape transformation of composite hydrogel sheet via erasable and rewritable nanoparticle patterns, ACS Appl. Mater. & Inter.,2019, In Revision.

  • 109. C.L. Yi, B. Liu, Y.Q. Yang, J. He,* Z.H. Nie*, Polymer-guided assembly of inorganic nanoparticles, Chem. Soc. Rev., 2019, In Revision.










Featured on Editors’ Highlights webpage of recent research on Organic Chemistry and Chemical Biology:



















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  • 35.  J. He, M. J. Hourwitz, Y.J. Liu, M. T. Perez, J., Z.H. Nie*, One-pot facile synthesis of Janus nanoparticles with tailored shape and functionality, Chem. Comm., 2011, 47, 12450-12452. 


  • 34.  E. Tumarkin, J.I. Park, Z.H. Nie*, E. Kumacheva*, Temperature-mediated generation of armoured bubbles, Chem. Comm., 2011, 47, 12712-12714.


     Publications from Toronto and Harvard​​​​

  • 33. O. Akbulut, C. R. Mace, R.V. Martinez, A. A. Kumar, Z.H. Nie, M.R. Patton, and G. M. Whiteside, Separation of Nanoparticles in Aqueous Multiphase Systems through Centrifugation, Nano Lett., 2012, 12 (8), 4060–4064.

  • 32. J. Lankelma*, Z.H. Nie, E. Carrilho, G.M. Whitesides, A Simple Paper-based Analytical Device for Electrochemical Flow Injection Analysis, Analytical Chemistry, 2012, 84 (9), 4147–415.

  • 31. E. Tumarkin, Z.H. Nie*, J.I. Park, M. Abdelhasani, J. Greener, B. Sherwood-Lollar, A. Guenther*, E.  Kumacheva*, Temperature-Controlled 'Breathing' of Carbon Dioxide Bubbles, Lab Chip 2011, 11, 3545-3550.

  • 30. K. Liu, Z.H. Nie, N.N. Zhao, M. Rubinstein, E. Kumacheva, Step-growth polymerization of inorganic nanoparticles, Science 2010, 329, 197-200.

  • 29. J.L. Gong, D.J. Lipomi, J.D. Deng, Z.H. Nie, N.X. Randall, R. Nair, G.M. Whitesides, Direct micro- and nano-patterning of planar substrates by indentation lithography, Nano Lett., 2010, 10, 2702–2708.

  • 28. A.W. Martinez, S.T. Phillips, Z.H. Nie, C.M. Cheng, E. Carrilho, B.J. Wiley, G.M. Whitesides,    Programmable diagnostic devices made from paper and tape, Lab Chip 2010, 10, 2499-2504.

  • 27. Z.H. Nie, F. Deiss, X.Y. Liu, G. M. Whitesides, Integration of paper-based microfluidic devices with commercial electrochemical readers, Lab Chip 2010, 10, 3163-3169.

  • 26. Z.H. Nie, C. Nijhuisa, J.L. Gong, X. Chen, A. Kumachev, A.W. Martineza, M. Narovlyanskya, G.M. Whitesides, Electrochemical sensing in paper-based microfluidic devices, Lab Chip 2010, 10, 477-483.

  • 25. J.I. Park, Z.H. Nie, A. Kumachev, E. Kumacheva, A microfluidic route to small CO2 microbubbles with narrow size distribution, Soft Matter 2010, 6, 630-634.

  • 24. Z.H. Nie, A. Petukhova, E. Kumacheva, Properties and emerging applications of self-assembled structures made from inorganic nanoparticles, Nat. Nanotech., 2010, 5, 15-25.

  • 23. N.N. Zhao, K. Liu, J. Greener, Z.H. Nie, E. Kumacheva, Close-packed super-lattices of side-by-side assembled Au-CdSe nanorods, Nano Lett., 2009, 9, 3077-3081.

  • 22. Z.H. Nie, D. Fava, E. Kumacheva, H.E. Ruda, A. Shik, Plasmon spectra in two-dimensional nanorod arrays, Nanotech. 2009, 20, 295203.

  • 21. J.I. Park, Z.H. Nie (co-first author), A. Kumachev, A.I. Abdelrahman, B.P. Binks, H.A. Stone, E. Kumacheva, A microfluidic approach to chemically driven assembly of colloidal particles at gas-liquid interfaces, Angew. Chem. Int. Ed. 2009, 48, 5300-5304.

  • 20. Z.H. Nie, M. Seo, S.Q. Xu, P.C. Lewis, M. Mokb, E. Kumacheva, P. Garsteckid, G.M. Whitesides, H.A. Stone, Emulsification in microfluidic flow-focusing device: effect of properties of liquids, Microfluidics and Nanofluidics 2008, 5, 585-594.

  • 19. Z.H. Nie, J.I. Park, W. Li, S.A.F. Bon, E. Kumacheva, Inside-out” microfluidic approach to producing monodisperse emulsion droplets stabilized by solid particles, J. Am. Chem. Soc. 2008, 130, 16508–16509.

  • 18. Z.H. Nie, E. Kumacheva, Patterning surfaces with functional polymers, Nat. Mater. 2008, 7, 277-290.

  • 17. Z.H. Nie, D. Fava, E. Kumacheva, M. Rubinstein, 'Supramolecular' assembly of gold nanorods end-terminated with polymer 'pom-poms': effect of the pom-pom structure, J. Am. Chem. Soc. 2008, 130, 3683-3689.

  • 16. D. Fava, Z.H. Nie, M. Winnik, E. Kumacheva, Evolution of self-assembled structures of polymer-terminated gold nanorods in selective solvents, Adv. Mater. 2008, 20, 4318-4322.  

  • 15. W. Li, E.W.K. Young, M. Seo, Z.H. Nie, P. Garstecki, C.A. Simmons, E. Kumacheva,  Simultaneous generation of droplets with different dimensions in parallel integrated droplet generators, Soft Matter, 2008, 4, 258-262.

  • 14. W. Li, H.H. Pham, Z.H. Nie, B. MacDonald, A. Guenther, E. Kumacheva, Multi-step microfluidic polymerization reactions conducted in droplets: the internal trigger approach, J. Am. Chem. Soc. 2008, 130, 9935-9941.

  • 13. S. Dubinsky, H. Zhang, Z.H. Nie, I. Gourevich, D. Voicu, M. Deetz, E. Kumacheva, Microfluidic synthesis of macroporous copolymer particles, Macromolecules 2008, 41, 3555-3561.

  • 12. Z.H. Nie, D. Fava, E. Kumacheva, S. Zou,  G.C. Walker., M. Rubinstein,  Self-assembly of metal-polymer analogues of amphiphilic triblock copolymers, Nat. Mater., 2007, 6, 609-614.

  • 11. M. Seo, C. Paquet, Z.H. Nie, S.Q. Xu, E. Kumacheva, Microfluidic consecutive flow-focusing droplet generators, Soft Matter, 2007, 3, 986-992.

  • 10. W. Li, Z.H. Nie, H. Zhang, C. Paquet, P. Garstecki, E. Kumacheva, Screening of the effect of surface energy of microchannels on microfluidic emulsification, Langmuir 2007, 23, 8010-8014.

  • 9. Z.H. Nie, W. Li,  M. Seo, S.Q. Xu, E. Kumacheva, Janus and ternary particles generated by microfluidic synthesis: Design, synthesis, and self-assembly, J. Am. Chem. Soc. 2006, 128, 9408-9412.

  • 8. H. Zhang, E. Tumarkin, R. Peerani, Z.H. Nie, R.M.A. Sullan, G.C. Walker., E. Kumacheva, Microfluidic production of biopolymer microcapsules with controlled morphology, J. Am. Chem. Soc., 2006, 128, 12205-12210.

  • 7. Z.H. Nie, S.Q. Xu, M. Seo, P.C. Lewis., E. Kumacheva, Polymer particles with various shapes and morphologies produced in continuous microfluidic reactors, J. Am. Chem. Soc. 2005, 127, 8058-8063.

  • 6. S.Q. Xu, Z.H. Nie, M. Seo, P.C. Lewis., E. Kumacheva, H.A. Stone, P. Garstecki, D.B. Weibel, I. Gitlin, G.M. Whitesides Generation of monodisperse particles by using microfluidics: Control over size, shape, and composition, Angew. Chem. Int. Ed. 2005, 44, 724-728.

  • 5. M. Seo, Z.H. Nie, S.Q. Xu, P.C. Lewis., R. Graham, M. Mok, E. Kumacheva, Continuous microfluidic reactors for polymer particles, Langmuir 2005, 21, 11614-11622.

  • 4. M. Seo, Z.H. Nie, S.Q. Xu, P.C. Lewis., E. Kumacheva, Microfluidics: from dynamic lattices to periodic arrays of polymer disks, Langmuir 2005, 21, 4773-4775.

  • 3. P.C. Lewis., R. Graham, Z.H. Nie, S.Q. Xu, M. Seo, E. Kumacheva, Continuous synthesis of copolymer particles in microfluidic reactors, Macromolecules 2005, 38, 4536-453.

  • 2. Z.H. Nie, Z.H. Su, Z.Y. Sun, T.F. Shi, L.J. An, Conformational study on thin films of symmetric A(n)B(2n)A(n) triblock copolymer, Macromolecular Theory and Simulations 2005, 14, 463-473.

  • 1. Z.H. Nie, T.F. Shi, L.J. An, A Monte Carlo simulation of morphology and structure for thin films of symmetric triblock copolymer after quenching and annealing, Chinese Journal of Chemistry 2004, 25, 1559-1562.